We demonstrated that GSTM2 protects against hepatic steatosis by inhibiting excess fat accumulation by interacting with and suppressing activation of apoptosis signal-regulating kinase1 ( ASK1 ) and subsequent p38-JNK signalling, besides its antioxidant capacity
In this study, an untargeted metabolomics approach based on liquid chromatography-mass spectrometry (LC-MS) was used to screen potential forensic biomarkers of fatal anaphylactic shock induced by four PENs (benzylpenicillin (BP), amoxicillin (AMX), oxacillin (OXA), and mezlocillin (MEZ)), and analyzed the metabolites, metabolic pathway and the mechanism which were closely related to the allergic reactions
In the use of L-asparaginase against cancer, glutamine depletion is associated with acute pancreatitis, hepatitis, thrombotic complication, and immune-suppression [44,45,46]
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